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Dr Anna Richardson

anna.richardson@srft.nhs.uk

Dr Anna Richardson completed her medical training at the University of Manchester, intercalating a BSc in pathology before specialising in Neurology. She was appointed Consultant Neurologist in 2002.

She has a long standing interest in the study of degenerative neurological disorders and spent a year as a research registrar in the Cerebral Function Unit as part of her neurology training. She now runs a specialist clinic within the Cerebral Function Unit. Dr Richardson's research interests include the genetic aspects of frontotemporal dementia and Alzheimer's disease.  She collaborates with Professor David Mann and Dr Stuart Pickering-Brown.

Publications

Baker M, Mackenzie IR, Pickering-Brown SM, Gass J, Rademakers R, Lindholm C, Snowden J, Adamson J, Sadovnick AD, Rollinson S, Cannon A, Dwosh E, Neary D, Melquist S, Richardson A, Dickson D, Berger Z, Eriksen J, Robinson T, Zehr C, Dickley CA, Crook R, McGowan E, Mann D, Boeve Bradley, Feldham H, Hutton M. Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17. Nature, 2006; 442: 916-919.

Davidson Y, Gibbons L, Pritchard A, Wren J, Tian J, Shi J, Stopford C, Julien C, Thompson J, Payton A, Thaker U, Hayes AJ, Iwatsubo T, Pickering-Brown SM, Pendleton N, Horan MA, Burns A, Purundare NB, Lendon CL, Neary D, Snowden JS, Mann DMA.  Genetic associations between cathepsin D exon 2 C>T polymorphism and Alzheimer’s disease and pathological correlations with genotype.  J. Neurol. Neurosurg. Psychiatry, 2006; 77, 515-517. 
 
Shi J, Shaw CL, Du Plessis D, Richardson AMT, Bailey KL, Julien C, Stopford C, Thompson J, Varma, A, Craufurd D, Tian J, Pickering-Brown S, Neary D, Snowden JS, Mann DMA. Histopathological changes underlying frontotemporal lobar degeneration with clinicopathological correlation. Acta Neuropathologica, 2006; 110: 501-12.

Srinivasan R, Davidson Y, Gibbons L, Payton A, Richardson AMT, Varma A, Julien C, Stopford C, Thompson J, Horan MA, Pendleton N, Pickering-Brown SM, Neary D, Snowden JS, Mann DMA. The apolipoprotein E  4 allele selectively increases the risk of frontotemporal lobar degeneration in males. J. Neurol. Neurosurg. Psychiatry, 2006; 77: 154 - 158.

Pickering-Brown S, Baker M, Bird T, Trojanowski J, Lee V, Morris H, Rossor M, Jannssen JC, Neary D, Craufurd D, Richardson A, Snowden J, Hardy J, Mann D, Hutton M. Evidence of a founder effect in families of frontotemporal dementia that harbour the tau +16 splice mutation. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 2004; 125B; 79-82.

Pickering Brown SM, Richardson AMT, Snowden JS, McDonagh AM, Burns A, Braude W, Baker M, Liu WK, Yen SH, Hardy J, Hutton M, Davies Y, Allsop D, Craufurd D, Neary D, Mann DMA. Inherited frontotemporal dementia in 9 British families associated with intronic mutations in the tau gene. Brain 2002; 125:732-751.